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Cytogenetic study of angiosarcoma of the breast

✍ Scribed by Dr. Rosario Gil-Benso; Concha López-Ginés; Pilar Soriano; Sergio Almenar; Carlos Vazquez; Antonio Llombart-Bosch

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
363 KB
Volume
10
Category
Article
ISSN
1045-2257

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✦ Synopsis

Angiosarcoma of the breast is quite rare, and the development of cutaneous angiosarcoma after segmental mastectomy and radiation therapy is even less common. A cytogenetic analysis of a mammary angiosarcoma arising in a breast after previous irradiation and segmental mastectomy for infiltrating ductal carcinoma revealed multiple clonal rearrangements involving chromosomes X, I, 2, 3,4, 5,6,7,8,9, IS, I7,20, and 22. No cytogenetically analyzed angiosarcomas of the breast have been reported before. Genes Chromosom Cancer /0:2 10-2 I2 (/994).

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## Abstract ## Background. The purpose of the study was to describe the clinicopathologic characteristics and clinical outcomes of patients with primary breast angiosarcoma. ## METHODS. The institutional database was searched to identify breast angiosarcoma patients seen between 1965 and 2002. S