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Cytogenetic localisation of the purine 1 and guanosine 1 loci of Drosophila melanogaster; the purine 1 locus specifies a vital function

✍ Scribed by Johnson, Merrie M. ;Woloshyn, E. P. ;Nash, David

Book ID: 104693231
Publisher: Springer
Year: 1979
Tongue: English
Weight: 489 KB
Volume: 174
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00267801

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✦ Synopsis

Three auxotrophic mutants at two loci (pur 1 and gua 1) apparently involved in purine metabolism were mapped cytologically to region 9E1-9E3 on the X-chromosome of Drosophila. Because mutants of pur 1 behaved as semi-lethals against deficiencies even on permissive medium, it appears that the pur 1 locus is vital to the fly and its auxotrophic mutants are hypomorphs.

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