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Cytogenetic investigations on a cell line derived from a carcinoma arising in a salivary gland pleomorphic adenoma

✍ Scribed by Jörn Bullerdiek; Karl-Josef Hutter; Günther Brandt; Margot Weinberg; Gazanfer Belge; Sabine Bartnitzke

Book ID
119104581
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
604 KB
Volume
44
Category
Article
ISSN
0165-4608

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A cultured cell line (CaPA-4). derived from an undifferentiated carcinoma in a pleomorphic adenoma of the submandibular gland, was established through xenografted tumors in nude mice. Geneticin treatment eliminated surrounding mouse fibroblasts and yielded enriched tumor cells at an early stage of c