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Cytogenetic heterogeneity in blast crisis (BC) of chronic myelogenous leukemia (CML)

โœ Scribed by Abramson, J. ;Verma, R. S. ;Schwartz, J.

Publisher
Springer-Verlag
Year
1985
Weight
282 KB
Volume
51
Category
Article
ISSN
1432-0584

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โœฆ Synopsis

New cytogenetic findings are reported in a patient who entered into an accelerated blastic phase of chronic myelogenous leukemia (CML). The cytogenetic findings of this case can be described as 46, xy, t (5;7) (q 31;q 11), t (9;22) (q 34;q 11), Ph'. The prognostic implications in such patients with rare and unusual cytogenetic findings are discussed.

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Blast crisis of Philadelphia chromosome-
Blast crisis of Philadelphia chromosome-positive chronic myelocytic leukemia (CML)
โœ Anger, B. ;Carbonell, F. ;Braunger, I. ;Heinze, B. ;Gutensohn, W. ;Thiel, E. ;He ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer-Verlag โš– 658 KB

We have studied the clinical courses of 69 patients with blastic crises of Philadelphia chromosome positive CML to identify parameters that were associated with an increased response rate or survival. Cytogenetic analysis at the time of blastic transformation revealed additional chromosome changes i