Screening of the occurrence of double minutes (DM) was performed in more than I ,OW metaphases obtained from a total of 22 solid human breast tumors and more than 3,600 metaphases from a total of 55 malignant effusions (45 patients with different types of carcinomas). D M were observed in I 5 of the
✦ LIBER ✦
Cytogenetic equivalents of gene amplification in cells of human carcinomas
✍ Scribed by E. Gebhart; S. Brüderlein
- Book ID
- 113251346
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 87 KB
- Volume
- 164
- Category
- Article
- ISSN
- 0165-1161
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## Abstract Gene amplification/overexpression was analyzed in 23 cell lines derived from human esophageal squamous‐cell‐carcinoma tissues by Southern and Northern hybridizations to c‐__myc__, c‐__erb__B, __hst__‐1 and __cyclin__‐DI probes. Amplification of the c‐__myc__ gene was observed in 5 cell