Earlier we reported that both actively replicating (A2 and B) and live but nonreplicating (C) strains of influenza virus induced significant percentages of chromosome aberrations in the spermatogonia of the infected mice, suggesting that virus replication was not essential for the induction of chrom
Cytogenetic effects of replicating and nonreplicating strains of influenza virus on male germ cells of mice
β Scribed by Menaka A. Thadani; Hanumanlu Polasa
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 311 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0340-6717
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β¦ Synopsis
Evidence is presented to demonstrate that replicating (A2 and B) and nonreplicating (C) strains of influenza virus were capable of inducing higher percentages of chromosomes anomalies in spermatocytes of mice inoculated either IP or IN than were seen in controls.
π SIMILAR VOLUMES
Swiss albino male mice were administered two doses (1 and 2 HA units) of influenza A2 Hong Kong/68 virus IP. The incidence of chromosomal anomalies in spermatocytes was analysed at various times post infection and was found to be significantly higher than in controls, indicating that the influenza v