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Cytogenetic effects of radiotherapy breakpoint distribution in induced chromosome aberrations

✍ Scribed by Leonardo Barrios; Rosa Miró; Maria Rosa Caballín; Carme Fuster; Ferràn Guedea; Antoni Subias; Josep Egozcue

Book ID
119104131
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
520 KB
Volume
41
Category
Article
ISSN
0165-4608

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Down syndrome (DS) individuals are known to be predisposed to develop leukemia and their lymphocytes are highly sensitive to the induction of chromosome aberrations by X-rays. A study was conducted to identify the chromosome breakpoints and to evaluate whether site specificity for chromosome breakag