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Cytogenetic effect of fecapentaene-12 in human lymphocytes

✍ Scribed by M. Bauchinger; E. Schmid

Book ID
113251649
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
167 KB
Volume
203
Category
Article
ISSN
0165-1161

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Cytogenetic effect of carboplatin on hum
Cytogenetic effect of carboplatin on human lymphocytes
✍ Tetsu Shinkai; Nagahiro Saijo; Kenji Eguchi; Yasutsuna Sasaki; Tomohide Tamura; πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 722 KB

Carboplatin, a second generation cisplatin analogue, was tested for induction of sister chromatid exchange (SCE) as well as chromosomal aberrations in human lymphocytes in vitro and in vivo. A dose-dependent effect was observed for increased frequency of metaphases with SCE (r = 0.984, P less than 0