## Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity, representing ˜90% of all oral carcinomas and accounting for 3–5% of all malignancies. The __WWOX__ gene (WW‐domain containing oxidoreductase) is a candidate tumor suppressor gene located at 16q
Cytogenetic demonstration of gene amplification in a primary intracranial germ cell tumor
✍ Scribed by Steffen Albrecht; Dawna L. Armstrong; Donald H. Mahoney; William R. Cheek; Linda D. Cooley
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 266 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1045-2257
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✦ Synopsis
W e report the cytogenetic analysis of a primary pineal germinoma. The modal chromosome number was 8 I. Multiple numerical and structural chromosome abnormalities were noted along with a large homogeneously staining region (HSR). No isochromosome I2p was identified.
📜 SIMILAR VOLUMES
Head and neck squamous cell carcinoma (HNSCC) affects nearly 500,000 individuals worldwide each year, with nearly 40,000 patients in the US alone. The 5-year survival rate is approximately 50%, and has not improved significantly in the past 20 years despite extensive efforts to increase cure rates.