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Cytogenetic and immunophenotypic evidence of independent clonal origins of concomitant chronic lymphocytic leukaemia and acute myeloid leukaemia

โœ Scribed by Maria Helena Ornellas de Souza; Teresa De Souza Fernandez; Hilda Rachel Diamond; Maria Christina Maioli; Paulo Cesar Pitanga Bacha; Stella Beatriz De Lucena


Book ID
119979588
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
43 KB
Volume
66
Category
Article
ISSN
0902-4441

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Deletions and translocations of 13q14 are the most frequent structural chromosome abnormalities found in chronic lymphocytic leukaemia (CLL). We have identified 13q14 translocations in the blood of 30 of 450 (6.6%) CLL patients by conventional cytogenetics, using tetradecanoyl phorbol 12-myristate 1