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Cytogenetic and fluorescence in situ hybridization characterization of chromosome 8 rearrangements in head and neck squamous cell carcinomas

✍ Scribed by Yuesheng Jin; Charlotte Jin; Johan Wennerberg; Mattias Höglund; Fredrik Mertens


Book ID
114135145
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
244 KB
Volume
130
Category
Article
ISSN
0165-4608

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Genomic heterogeneity has been observed in several solid tumor types. To investigate this phenomenon in head and neck squamous cell carcinoma (HNSCC), we analyzed macroscopically distinct tissue samples of 12 resected tumors by a combination of fluorescence in situ hybridization (FISH) and DNA flow