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Cytogenetic analysis of three primary Bellini duct carcinomas

✍ Scribed by M. Aurelia Gregori-Romero; Luisa Morell-Quadreny; Antonio Llombart-Bosch

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
204 KB
Volume
15
Category
Article
ISSN
1045-2257

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✦ Synopsis

Three Bellini duct carcinomas (BDC) of the kidney were cytogenetically analyzed after short-term culture. All three had clonal chromosome abnormalities: 9 I-92,XXY,-Y, + 12, + 12,-15,-16,-18, + mar (case I); 53,XY, + 2,t(2;7)(p22;q I I), + der(2)t (2;7)(p22;q I I ), + 3. + r(3),add( 5)(p I 5), + 7,-8, + I 2, + I 7, + r( I 7), + 20,-2 I (case 2); and 44-47,X.-Y, + 9, + 16, -2 I /46,XY. Some of the numerical abnormalities are shared with papillary renal cell carcinomas (PRCC)( + 7, + 12, + 16, + 17, and + 20) but not with transitional renal cell carcinomas. The present findings support the previous notion that BDC are different from other types of RCC.

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