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Cytogenetic analysis of in vitro karyotype evolution in a cell line established from nonmalignant human mammary epithelium

✍ Scribed by Kirsten Vang Nielsen; Per Briand


Book ID
119104246
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
671 KB
Volume
39
Category
Article
ISSN
0165-4608

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The immortalized, nontumorigenic human breast epithelial cell line HMT-3522 has been used as a model for premalignant and, eventually, malignant development. During cultivation, the karyotype evolution was followed. At an early stage, a very long constant phase showed a near-diploid karyotype, with