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Cytofluorometric DNA ploidy analysis in giant cell tumor of bone: histologic and prognostic value

✍ Scribed by Hiroaki Murata; Katsuyuki Kusuzaki; Hideyuki Takeshita; Masazumi Hirata; Shin Hashiguchi; Tsukasa Ashihara; Yassusuke Hirasawa

Book ID
117469303
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
284 KB
Volume
136
Category
Article
ISSN
0304-3835

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## Abstract Genetic instability in relation to clinical behavior was studied in 52 cases of giant cell tumor of bone (GCTB). Ploidy was determined in the mononuclear cell population by using native cell smears and image cytometry. A relocalization technique allowed fluorescent in situ hybridization