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Cytochrome P450 interactions and clinical implication in rheumatology

✍ Scribed by Cayot, Audrey; Laroche, Davy; Disson-Dautriche, Anne; Arbault, Anaïs; Maillefert, Jean-Francis; Ornetti, Paul


Book ID
124095703
Publisher
Springer
Year
2014
Tongue
English
Weight
196 KB
Volume
33
Category
Article
ISSN
0770-3198

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The magnitude of drug±drug interactions in vitro involving competitive inhibition of cytochrome (CYP) isozymes by newer antidepressants can theoretically be shown to be dependent upon several factors. These include the concentration of both the substrate and inhibitor, the anity of the inhibitor for