The interaction of antiparasitic drugs with the polymorphic cytochrome P450 2D6 was studied in human liver microsomes. Of ten different drugs tested, three quinolines, oxamniquine, primaquine and chloroquine inhibited microsomal CYP2D6-catalysed formation of l'hydroxybufuralol at concentrations tha
Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry
β Scribed by UlrichM. Zanger; Sebastian Raimundo; Michel Eichelbaum
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 449 KB
- Volume
- 369
- Category
- Article
- ISSN
- 0028-1298
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