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Cytochrome P450 1B1 gene mutations in Japanese patients with primary congenital glaucoma

โœ Scribed by Tomoko Kakiuchi-Matsumoto; Yasushi Isashiki; Norio Ohba; Katsuaki Kimura; Shozo Sonoda; Kazuhiko Unoki


Book ID
117017508
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
248 KB
Volume
131
Category
Article
ISSN
0002-9394

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Novel cytochrome P450 1B1 (CYP1B1) mutat
โœ Evelyne Colomb; Josseline Kaplan; Henri-Jean Garchon ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 31 KB

The CYP1B1 gene (GenBank: U56438), a member of the cytochrome P450 gene family, has been shown to be mutated in patients with primary congenital glaucoma (PCG), a rare but severely blinding form of glaucoma. Here, we have investigated CYP1B1 mutations in 31 unrelated French PCG patients. Mutations w