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Cytochrome P3A4 Inhibitors and Other Constituents of Fibraurea tinctoria

โœ Scribed by Su, Chung-Ren; Ueng, Yune-Fang; Dung, Nguyen Xuan; Vijaya Bhaskar Reddy, M.; Wu, Tian-Shung

Book ID
127002634
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
82 KB
Volume
70
Category
Article
ISSN
0163-3864

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โœ Andrea Dreiseitel; Peter Schreier; Anett Oehme; Sanja Locher; Goeran Hajak; Phil ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 338 KB

## Abstract The cytochrome P450 enzyme cytochrome P450 3A4 (CYP3A4) controls the metabolism of about 60% of all drugs, and its inhibition may dramatically affect drug safety. Modulation of cytochrome P450 activity has been observed by constituents of fruit extracts including several flavonoids. The