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Cytochrome c dissolved in 1-allyl-3-methylimidazolium chloride type ionic liquid undergoes a quasi-reversible redox reaction up to 140°C

✍ Scribed by Kaori Tamura; Nobuhumi Nakamura; Hiroyuki Ohno


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
899 KB
Volume
109
Category
Article
ISSN
0006-3592

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✦ Synopsis


Abstract

Solubility of cytochrome c, a typical heme protein, in a various ionic liquids has been analyzed. The solubility has been discussed with polarity parameters of the ionic liquids. Both hydrogen bond basicity and dipolarity/polarizability of the ionic liquids were confirmed to be influential factors to control the solubilization of cytochrome c. Polar ionic liquids such as 1‐butyl‐3‐methylimidazolium chloride and 1‐allyl‐3‐methylimidazolium chloride solubilized cytochrome c at 80°C, and the dissolved cytochrome c was found to keep its redox activity in these ionic liquids. The redox response of the dissolved cytochrome c was detected in 1‐allyl‐3‐methylimidazolium chloride up to 140°C. Biotechnol. Bioeng. 2012; 109:729–735. © 2011 Wiley Periodicals, Inc.