Cytochrome c and dATP-Dependent Formatio
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Peng Li; Deepak Nijhawan; Imawati Budihardjo; Srinivasa M Srinivasula; Manzoor A
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Article
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1997
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Elsevier Science
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English
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We report here the purification of the third protein factor, Apaf-3, that participates in caspase-3 activation in vitro. Apaf-3 was identified as a member of the caspase family, caspase-9. Caspase-9 and Apaf-1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the prese