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Cyto-insectotoxins, a novel class of cytolytic and insecticidal peptides from spider venom

✍ Scribed by Vassilevski, Alexander A.; Kozlov, Sergey A.; Samsonova, Olga V.; Egorova, Natalya S.; Karpunin, Dmitry V.; Pluzhnikov, Kirill A.; Feofanov, Alexei V.; Grishin, Eugene V.

Book ID
120505195
Publisher
Portland Press
Year
2008
Tongue
English
Weight
459 KB
Volume
411
Category
Article
ISSN
0264-6021

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Fractionation of venom from an agelenid spider, Tegenaria agrestis, resulted in the isolation of a family of three peptides with potent insecticidal activity. These peptide toxins, TaITX-1, -2, and -3, whose sequences were revealed from cloned cDNAs, each consist of 50 amino acid residues, six of wh