Cystic fibrosis—correct chloride conductance can cure cells

✍ Scribed by Rebecca W. van Dyke

• Book ID: 102852112
• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 549 KB
• Volume: 14
• Category: Article
• ISSN: 0270-9139
• DOI: 10.1002/hep.1840140134

✦ Synopsis

We have used retrovirus-mediated gene transfer to demonstrate complementation of the cystic fibrosis (CF) defect in vitro. Amphotropic retroviruses were used to transduce a functional cystic dbrosis transmembrane conductance regulator (CFTR) cDNA into