Cystic fibrosis-related diabetes mellitus: clinical impact of prediabetes and effects of insulin therapy
β Scribed by MA Rolon; K Benali; A Munck; J Navarro; A Clement; N Tubiana-Rufi; P Czernichow; M Polak
- Book ID
- 114812957
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 198 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0803-5253
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## Abstract Pancreatic endocrine dysfunction in patients with cystic fibrosis heralds declining pulmonary function and a sixβfold rise in mortality. Insulin therapy increases weight and reduces decline in lung function. Optimal timing of initiation remains contentious but early intervention may max
## Abstract In cystic fibrosis, gradual pancreatic destruction causes progressive insulin deficiency, culminating in cystic fibrosis related diabetes (CFRD). As a consequence of insulin deficiency, elevated glucose levels can be detected (well before the diagnosis of CFRD), by continuous ambulatory