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Cysteine-Rich and Basic Domain HIV-1 Tat Peptides Inhibit Angiogenesis and Induce Endothelial Cell Apoptosis

โœ Scribed by Haiyan Jia; Marianne Lohr; Sylvie Jezequel; Dana Davis; Shaheda Shaikh; David Selwood; Ian Zachary


Book ID
115587866
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
544 KB
Volume
283
Category
Article
ISSN
0006-291X

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Kaposi's sarcoma (KS), a neoplasm often associated with iatrogenic and acquired immunosuppression, is characterized by prominent angiogenesis. Angiogenic factors released by both KS and host cells, as well as HHV-8 and HIV viral products, have been implicated in the pathogenesis of this lesion. Angi