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Cysteine cathepsin proteases as pharmacological targets in cancer

✍ Scribed by Carmela Palermo; Johanna A. Joyce


Book ID
116918766
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
152 KB
Volume
29
Category
Article
ISSN
0165-6147

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## Abstract The aim of this study was to determine the involvement of cathepsin B and its inhibitors in the proteolytic degradation of human osteoarthritic (OA) tissue. The characteristics of the cathepsin B found in both normal and OA cartilage and synovium were similar to those of the lysosomal c