## Abstract Estrogen deficiency causes osteoporosis via increased generation of reactive oxygen species (ROS), and thus, antioxidants may prove to be the effective therapeutic candidates. We examined the effects of the antioxidant __N__βacetylcysteine (NAC) on osteoblastic differentiation in mouse
β¦ LIBER β¦
Cystatin C stimulates the differentiation of mouse osteoblastic cells and bone formation
β Scribed by Atsushi Danjo; Takayoshi Yamaza; Mizuho A. Kido; Daiji Shimohira; Takayuki Tsukuba; Tadayoshi Kagiya; Yoshio Yamashita; Katsushi Nishijima; Sadahiko Masuko; Masaaki Goto; Teruo Tanaka
- Book ID
- 116295184
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 333 KB
- Volume
- 360
- Category
- Article
- ISSN
- 0006-291X
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Osteoporosis is defined as reduced bone mineral density with a high risk of fragile fracture. Current available treatment regimens include antiresorptive drugs such as estrogen receptor analogues and bisphosphates and anabolic agents such as parathyroid hormone (PTH). However, neither option is comp