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Cystathionine β synthase participates in murine oocyte maturatione mediated by homocysteine

✍ Scribed by Rong Liang; Wei-Dong Yu; Jun-Bao Du; Li-Jun Yang; Jing-Jing Yang; Jian Xu; Mei Shang; Jing-Zhu Guo


Book ID
113875147
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
700 KB
Volume
24
Category
Article
ISSN
0890-6238

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High homocysteine (HCY) levels are a risk factor for osteoporotic fracture. Furthermore, bone quality and strength are compromised by elevated HCY owing to its negative impact on collagen maturation. HCY is cleared by cystathionine b-synthase (CBS), the first enzyme in the transsulfuration pathway.