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CYP46A1T/C polymorphism associated with theAPOEε4allele increases the risk of Alzheimer’s disease

✍ Scribed by Ling Li, Zegang Yin, Juan Liu, Gongbo Li, Yanjiang Wang…


Book ID
120898408
Publisher
Springer
Year
2012
Tongue
English
Weight
525 KB
Volume
260
Category
Article
ISSN
0340-5354

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The apolipoprotein E ε2 allele is associ
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It was suggested that in contrast to the E4 allele, the E2 allele of the apolipoprotein E gene (APOE"2) has a protective effect for late-onset Alzheimer's disease and early-onset Alzheimer's disease (EOAD). We studied the role of the APOE\*2 allele in the pathogenesis of EOAD in a Dutch population-b