In order to identify single nucleotide polymorphisms (SNPs) and haplotype frequencies of CYP3A5 in a Japanese population, we sequenced the proximal promoter region, all exons, and the surrounding intronic regions using genomic DNA from 187 Japanese subjects. Thirteen SNPs, including seven novel ones
β¦ LIBER β¦
CYP3A5*3and*6single nucleotide polymorphisms in three distinct Asian populations
β Scribed by C. Balram; Qingyu Zhou; Yin Bun Cheung; Edmund J. D. Lee
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 170 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0031-6970
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## Abstract ## Objective Genomeβwide association (GWA) studies in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) in Caucasian populations have independently identified risk variants in and near the tumor necrosis factor Ξ± (TNFΞ±)βinduced protein 3 gene (__TNFAIP3__), which is cruc