Prediction of response to docetaxel by C
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Yasuo Miyoshi; Akiko Ando; Yuuki Takamura; Tetsuya Taguchi; Yasuhiro Tamaki; Shi
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Article
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2001
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John Wiley and Sons
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French
β 94 KB
## Abstract We studied the relationship between response of breast cancer to docetaxel (DOC) or cylophosphamide + epirubucin (CE) treatment and CYP3A4 mRNA expression in breast tumors. CYP3A4 inactivates DOC but not E, which is a predominant effector in CE treatment. Twenty patients with locally ad