๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

CYP2E1-Dependent Bioactivation of 1,1-Dichloroethylene in Murine Lung: Formation of Reactive Intermediates and Glutathione Conjugates

โœ Scribed by Taylor F. Dowsley; Judith B. Ulreich; Judy L. Bolton; Sang S. Park; Poh-Gek Forkert


Book ID
112266128
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
104 KB
Volume
139
Category
Article
ISSN
0041-008X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Conjugation of glutathione with the reac
โœ Forkert, Poh-Gek ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 852 KB

Exposure to 1,1-dichloroethylene (DCE) elicits lung and liver cytotoxicities that are manifested in bronchiolar Clara cell injury and centrilobular necrosis, respectively. The tissue damage is associated with cytochrome P450-dependent bioactivation of DCE to reactive intermediates, and is consistent