Characterization of a novel CYP2A7/CYP2A
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Mikael Oscarson; Roman A. McLellan; Vendela Asp; MariCarmen Ledesma; Maria Luisa
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Article
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2002
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John Wiley and Sons
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English
β 191 KB
The human CYP2A6 enzyme metabolizes certain drugs and pre-carcinogens and appears to be the most important enzyme for nicotine metabolism. At present, more than 10 different allelic variants are known that cause abolished or decreased enzyme activity. Genetic polymorphism in this gene might be of pa