## Abstract Genetic backgrounds may modify the association of environmental tobacco smoke (ETS) with lung cancer risk. Polymorphisms of both the activating and detoxifying enzymes, cytochrome P4501A1 (CYP1A1) and glutathioneβSβtransferase M1 (GSTM1), may be important as genetic factors. We conducte
CYP1A1polymorphisms and risk of lung cancer in non-smoking Chinese women: influence of environmental tobacco smoke exposure andGSTM1/T1genetic variation
β Scribed by Daniel P. K. Ng; Kar-Wai Tan; Bin Zhao; Adeline Seow
- Publisher
- Springer Netherlands
- Year
- 2005
- Tongue
- English
- Weight
- 212 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0957-5243
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Endogenous estrogen and tobacco smoke are putative risk factors for breast cancer. The genes CYP1A1 and 1B1 are involved in the metabolism of endogenous estrogen as well as of tobacco specific compounds. In a German population based case-control study of premenopausal breast cancer risk with 394 cas
The association between exposure to ETS and the risk of lung cancer in life-time non-smoking women was investigated by means of a hospital based case-control study in Moscow, Russia. The main importance of our study is that it was conducted on a population with a specific smoking pattern from which
## Abstract ## __Background.__ UGT1A7 is an enzyme involved in the metabolism of (pre)carcinogens present in tobacco smoke. We investigated whether genetic polymorphisms in __UGT1A7__, with predicted altered enzyme activity, may have a riskβmodifying effect on head and neck carcinogenesis. ## __M
There is no direct evidence that workplace environmental tobacco smoke (ETS) increases lung cancer risk Demands for regulation of workplace smoking are based on studies reporting increased risk in non-smoking women whose husbands smoke Although denying smoking can artificially elevate risk estimates