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CYP17 T27C polymorphism and prostate cancer risk: a meta-analysis based on 31 studies

✍ Scribed by Bingbing Wei; Yunyun Zhang; Bo Xi; Junkai Chang; Jinming Bai; Jiantang Su


Book ID
117802874
Publisher
Journal of Biomedical Research
Year
2010
Tongue
English
Weight
416 KB
Volume
24
Category
Article
ISSN
1674-8301

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## Abstract Because androgens likely play a key role in prostate growth and prostate cancer development, variants of genes involved in androgen biosynthesis may be related to prostate cancer risk. The enzyme P450c17Ξ±, encoded by the __CYP17__ gene, catalyzes the conversion of progesterone and pregn