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CYP17 genetic polymorphism in endometrial cancer: are only steroids involved?

โœ Scribed by Lev M Berstein; Evgeny N Imyanitov; Vera B Gamajunova; Anatolij Ju Kovalevskij; Ekatherina Sh Kuligina; Evgeniya V Belogubova; Konstantin G Buslov; Maria B Karpova; Alexandr V Togo; Oleg N Volkov; Irina G Kovalenko

Book ID
117467288
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
86 KB
Volume
180
Category
Article
ISSN
0304-3835

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Genetic polymorphisms of CYP2D6*10 and C
Genetic polymorphisms of CYP2D6*10 and CYP2C19*2, *3 are not associated with prognosis, endometrial thickness, or bone mineral density in Japanese breast cancer patients treated with adjuvant tamoxifen
โœ Matthew Goetz; Vera Suman ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 56 KB ๐Ÿ‘ 1 views

The study by Okishiro et al 1 concludes that the cytochrome P450 (CYP) genotype CYP2D6\*10/\*10 is unlikely to have a clinically significant impact on prognosis in women with breast cancer who receive adjuvant tamoxifen. However, several aspects of the study by Okishiro et al call their conclusions