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CYP17 gene polymorphism and its association with high-risk north Indian breast cancer patients

✍ Scribed by Anurupa Chakraborty; N. S. Murthy; Chintamani Chintamani; D. Bhatnagar; R. S. Mohil; P. C. Sharma; Sunita Saxena

Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
195 KB
Volume
52
Category
Article
ISSN
1435-232X

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Long-term exposure to oestrogens is a well-recognised risk factor for breast cancer, whereas little is known about the influence of polymorphisms of genes involved in oestrogen biosynthesis and metabolism. A candidate, containing a single bp polymorphism, T8C, (designated, A2 allele), might be the C