Cyclosporine uptake by cultured human proximal tubule cells
β Scribed by Myong Won Kahng; Jung Young Lee; Anna L. Trifillis
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 423 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0272-4391
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The growth of rat kidney proximal tubule cells was monitored continuously by the cellular incorporation of [methylβ^14^C] thymidine using scintillating microplates. The radioisotope had no effect on cell proliferation over a 5 day period, neither was it extensively converted to thymine. Leibovitz Lβ
## Abstract Cyclosporine A (CsA) is known to have direct toxicity to renal tubular cells. Its toxicity may be mediated by intracellular calcium because CsA increases intracellular calcium concentration and enhances the activities of calciumβdependent calpains and caspases. CalbindinβD~28k~, a cytos
## Abstract We have examined the effect of dopamine on Ca^2+^ uptake and its related signaling pathways in primary renal proximal tubule cells (PTCs). Dopamine increased Ca^2+^ uptake in a concentration (>10^β10^ M) and timeβ (>8 h) dependent manner. Dopamineβinduced increase in Ca^2+^ uptake was p
## Abstract Suspensions of rat kidney cells obtained by disaggregation of the kidney with 0.25% trypsin were separated by electrophoresis. Previously, we found a correlation between cells with histochemically demonstrable alkaline phosphatase (HDAP) and cells with brush borders which established th
Uptake of ['Hltaurine, ["Sjhypotaurine, and ['H]y-arninobutyric acid (GABA) was studied in ncuroblastoma C 1300 cells in Krebs-Ringer-Hepes-glucose medium (pH 7.4). The uptakes consisted of nonsaturable penetration (taurine and hypotaurine) and two saturable transport components: high affinity for t