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Cyclosporine pharmacokinetics and effect in the Type I diabetic rat model

✍ Scribed by L. J. Brunner; L. V. Iyer; K. Vadiei; W. V. Weaver; D. R. Luke

Book ID
113006733
Publisher
Springer-Verlag
Year
1989
Tongue
English
Weight
711 KB
Volume
14
Category
Article
ISSN
0378-7966

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## Abstract The immunosuppressive effects of 2Β·5 (__n__ = 6) and 5 mg kg^βˆ’1^ day^βˆ’1^ (__n__ = 7) of cyclosporine (CSA) given intravenously for 9 days to the immunized, hyperlipidemic Zucker rat model were compared with drug‐free animals (__n__ = 6) and lean litter‐mates given 0 (__n__ = 6), 5 (__n_