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Cyclosporine A enhances renin secretion and production in isolated juxtaglomerular cells

✍ Scribed by Kurtz, Armin; Bruna, Roberto Della; Kühn, Karlwilhelm


Book ID
109881209
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
568 KB
Volume
33
Category
Article
ISSN
0085-2538

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Amiloride enhances the secretion but not
✍ Armin Kurtz; Roberto Bruna; Holger Scholz; Wolfgang Baier 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 670 KB

In this study we have examined a potential role of the sodium/proton exchange system in the regulation of renin secretion. We found that the inhibitors of the Na+/H + antiport, amiloride (1 mM) and ethylisopropylamiloride (EIPA, 50 ~tM), led to a 125% increase of renin secretion from cultured mouse