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Cyclosporin A induces apoptosis in H9c2 cardiomyoblast cells through calcium-sensing receptor-mediated activation of the ERK MAPK and p38 MAPK pathways

✍ Scribed by Chi, Jinyu; Zhu, Yejing; Fu, Yu; Liu, Yue; Zhang, Xiaohui; Han, Lei; Yin, Xinhua; Zhao, Dechao

Book ID
113075278
Publisher
Springer
Year
2012
Tongue
English
Weight
629 KB
Volume
367
Category
Article
ISSN
0300-8177

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## Abstract Caffeine attenuated invasion of human leukemia U937 cells with characteristic of decreased protein expression and mRNA levels of matrix metalloproteinase‐2 (MMP‐2) and MMP‐9. Down‐regulation of MMP‐2 and MMP‐9 in U937 cells was abrogated by abolishment of caffeine‐elicited increase in i