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Cyclosporin A and tacrolimus (FK506) suppress expression of inducible nitric oxide synthase in vitro by different mechanisms

✍ Scribed by Gregory J Dusting; Kazuhiro Akita; Haruyo Hickey; Melanie Smith; Vladimir Gurevich


Book ID
110004524
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
332 KB
Volume
128
Category
Article
ISSN
0007-1188

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Expression of inducible nitric oxide syn
✍ N. Onier; S. Hilpert; S. Reveneau; L. Arnould; V. Saint-Giorgio; J.M. Exbrayat; πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 349 KB πŸ‘ 2 views

It is well documented that nitric oxide (NO) is an effector molecule of macrophage-mediated tumor cell toxicity in vitro; however, little is known about the role of NO in the antitumor immune response in vivo. We have developed a treatment protocol using lipid A. We have investigated the effects of