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Cyclosporin A and FK506 Inhibit Activation-Induced Cell Death in the Murine WEHI-231 B Cell Line

✍ Scribed by Laurent Genestier; Marie Therese Dearden-Badet; Nathalie Bonnefoy-Berard; Gerard Lizard; Jean Pierre Revillard

Book ID
112238963
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
316 KB
Volume
155
Category
Article
ISSN
0008-8749

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Cyclosporin A and FK-506 in inhibition o
Cyclosporin A and FK-506 in inhibition of rat ito cell activation in vitro
✍ Hitoshi Ikeda; Kenji Fujiwara πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 652 KB

Ito cells are the primary matrix-producing cells in the liver. In hepatic fibrosis in uiuo or culture on plastic, these cells undergo activation, a process characterized by cell proliferation, fibrogenesis, and smooth muscle a- actin expression. The cytosolic-binding proteins of cyclosporin A (CsA)