## Abstract Past surveys indicated that the occurrence of aflatoxins, zearalenone and ochratoxin A was not a problem in corn and corn products in the state of SΓ£o Paulo, Brazil. However, according to recent studies, a change in pattern has been detected. To obtain a better overview, these toxins we
Cyclopiazonic acid in combination with aflatoxins, zearalenone and ochratoxin A in Indonesian corn
β Scribed by R. Widiastuti; R. Maryam; B. J. Blaney; Salfina; D. R. Stoltz
- Publisher
- Springer Netherlands
- Year
- 1988
- Tongue
- English
- Weight
- 320 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0301-486X
No coin nor oath required. For personal study only.
β¦ Synopsis
The mycotoxin, cyclopiazonic acid (CPA), was detected at concentrations as high as 9 ppm in 21 of 26 corn samples from a Bogor poultry feedmill. This is the first demonstration of the natural occurrence of CPA in Indonesia. CPA was always accompanied by other mycotoxins, especially aflatoxins, suggesting that the interactive toxicity of these mycotoxins to poultry should be investigated.
π SIMILAR VOLUMES
Cyclopiazonic acid (CPA) and aflatoxin are known sometimes to coexist in nature but little is known of possible biological interaction in mammals that consume mixtures of these two mycotoxins. Guinea pigs were dosed orally with CPA (2.2 mg/kg) or aflatoxin (0.045 mg B1/kg ) singly or in combination.
## Abstract Aflatoxin B1 (AFB1) and ochratoxin A (OTA) are important foodβborne mycotoxins that have been implicated in human health. In this study, independent and combinative toxicities of AFB1 and OTA were tested in cultured monkey kidney Vero cells. The experiments reported here were conducted