Cyclophosphamide-induced ovarian failure and its therapeutic significance in patients with breast cancer
β Scribed by Hiroki Koyama; Tomio Wada; Yukio Nishizawa; Takeshi Iwanaga; Yukitoshi Aoki; Toshio Terasawa; Goro Kosaki; Toshihide Yamamoto; Akira Wada
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 440 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. The authors combined cisplatin and carboplatin together with cyclophosphamide to maximize platinum dose intensity in patients with advanced epithelial ovarian cancer (AOC). ## METHODS. The authors treated 26 consecutive, newly diagnosed patients with International Federation of G
Data on 162 women (90 premenopausal and 72 postmenopausal) with metastatic breast cancer randomized to receive cyclophosphamide, Adriamycin (doxorubicin) and 5-fluorouracil (CAF) on two Eastern Cooperative Oncology Group (ECOG) protocols were analyzed. Twenty-three percent had complete remission; 39