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Cyclophosphamide in the treatment of multiple myeloma

✍ Scribed by Salokannel, S. J. ;Palva, I. P. ;Timonen, T. ;Kaipainen, W. J.

Publisher
Springer-Verlag
Year
1971
Weight
251 KB
Volume
23
Category
Article
ISSN
1432-0584

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## METHODS. Four hundred seventy-nine previously untreated patients with multiple myeloma from 23 ECOG institutions were enrolled. Treatment, assigned by ran-1 The Virginia Piper Cancer Institute and the Unidomization, consisted of either 4-week cycles of MP or 5-week cycles of VBCMP.

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## BACKGROUND. Interferon (IFN) has demonstrated activity in the treatment of patients with multiple myeloma. A previous Eastern Cooperative Oncology Group (ECOG) study suggested that the rates of complete response (CR) and survival were increased with a regimen that alternated IFN with chemothera