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Cyclopentenone Eicosanoids as Mediators of Neurodegeneration: A Pathogenic Mechanism of Oxidative Stress-Mediated and Cyclooxygenase-Mediated Neurotoxicity

✍ Scribed by Erik S. Musiek; Ginger L. Milne; Beth Ann McLaughlin; Jason D. Morrow


Book ID
111404349
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
212 KB
Volume
15
Category
Article
ISSN
1015-6305

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## Interleukin-1 beta (IL-1␀ ) is an inflammatory cytokine whose expression is elevated in brain during seizures, ischemia, and injury. Expression of IL-1␀ and its receptor can also be observed in normal brain. Platelet-activating factor (PAF) is also a dual mediator that promotes neuronal plastici