## Abstract ## Background and Objectives Elevated expression of cyclooxygenaseโ2 (COXโ2) has been established to be a feature of breast cancer. There has been inconsistency in the literature regarding the precise significance of thisโsome studies have found no clinicopathological relevance at all,
Cyclooxygenase-2 expression: a potential prognostic and predictive marker for high-grade ductal carcinoma in situ of the breast
โ Scribed by K-B Tan; W-P Yong; T C Putti
- Book ID
- 108778844
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 166 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0309-0167
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he management of patients with ductal carcinoma in situ (DCIS) of
## Abstract ## BACKGROUND Cyclooxygenases regulate the production of prostaglandins and play a role in tumor development and progression. The authors investigated the prognostic impact of expression of the cyclooxygenase (COX) isoforms, COXโ1 and COXโ2, on diseaseโfree survival and progressionโfre
## Abstract ## BACKGROUND A number of conventional histopathologic features have been associated with recurrence of ductal carcinoma in situ (DCIS) after surgery alone and are included in the Van Nuys Pathologic Classification and Prognostic Index. To the authors' knowledge, very little is known r