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Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes

✍ Scribed by Miyako Kato; Shinichi Nishida; Hidero Kitasato; Natsue Sakata; Shinichi Kawai

Book ID
111768783
Publisher
Pharmaceutical Press
Year
2001
Tongue
English
Weight
224 KB
Volume
53
Category
Article
ISSN
2042-7158

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Apoptosis induction and cyclooxygenase-2 regulation in human colorectal adenoma and carcinoma cell lines by the cyclooxygenase-2-selective non-steroidal anti-inflammatory drug NS-398
✍ Douglas J.E. Elder; Dawn E. Halton; Tracey E. Crew; Christos Paraskeva πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 French βš– 226 KB πŸ‘ 2 views

We determined the effect of the highly selective cyclooxygenase-2 (COX-2) inhibitor NS-398 on proliferation, apoptosis and COX-2 regulation in 3 pre-malignant human colorectal adenoma cell lines (RG/C2, AA/C1, RR/C1) and compared its effect on 3 colorectal carcinoma cell lines (HT29, KS, JW2). COX-2