Cycloisomerization of Alkynols at Transition Metal Templates

✍ Scribed by Bernd Weyershausen; Karl Heinz Dötz

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 384 KB
• Volume: 1999
• Category: Article
• ISSN: 1434-1948
• DOI: 10.1002/(sici)1099-0682(199907)1999:7<1057::aid-ejic1057>3.0.co;2-9

✦ Synopsis

The metal-assisted cycloisomerization of ω-alkynols to oxa-and -hexynols to give the corresponding oxacycloalkylidene complexes. In some cases kinetic hydroxyalkylvinylidene cycloalkylidene complexes is reviewed. A variety of low-valent coordinatively unsaturated transition metal templates from complex intermediates can be isolated and characterized. group 6 to 10 mediate the cyclization of ω-butynols, -pentynols, [a] Kekule ´-Institut für Organische Chemie und Biochemie, Fischer-type carbene complexes is still based on the two-Gerhard-Domagk-Straße 1, D-53121 Bonn, Germany step addition of a nucleophile and an electrophile across