Cycloheximide abolishes pertussis toxin-induced increase in glutamate release from cerebellar granule neurones
β Scribed by Cullen, Grainne P.; Huston, Elaine; Dolphin, Annette C.
- Book ID
- 123020234
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 619 KB
- Volume
- 166
- Category
- Article
- ISSN
- 0304-3940
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Excess administration of glutamate is known to induce Ca 21 overload in neurons, which is the first step in excitotoxicity. Although some reports have suggested a role for Mg 21 in the excitotoxicity, little is known about its actual contribution. To investigate the role of Mg 21 in the excitotoxici
The properties of depolarizationevoked calcium transients are known to change during the maturation of dissociated cerebellar granule neuron cultures. Here, we assessed the role of the calciuminduced calcium release (CICR) mechanism in granule neuron maturation. Both depletion of intracellular calci